IHydroxypropyl methylcellulose (igama le-INN: iHypromellulose), ekwafinyezwa njenge-hydroxypropyl methylcellulose (HPMC), luhlobo lwe-non-ionic cellulose exutyiweyo ethers.

IHydroxypropyl methylcellulose(Igama le-INN:Hypromelulose), nayo ishunqulelwe njengeihydroxypropyl methylcellulose (HPMC), luhlobo lwe-non-ionic cellulose exutywe ii-ethers. Yi-semi synthetic, engasebenziyo, i-viscoelastic polymer edla ngokusetyenziswa njenge-lubricant kwi-ophthalmology, okanye njenge-adjunct okanye i-excipient kumayeza omlomo, ehlala ifumaneka kwiindidi ezahlukeneyo zeemveliso.

Njengesongezo sokutya, i-hydroxypropyl methylcellulose inokudlala indima elandelayo: i-emulsifier, i-thickener, i-agent yokumisa, kunye ne-substitute ye-gelatin yezilwanyana. Ikhowudi yayo yeCodex Alimentarius yi-E464.

ipropati yeekhemikhali

Imveliso egqityiweyo yei-hydroxypropyl methyl cellulosengumgubo omhlophe okanye omhlophe okhululekileyo oqinileyo, kunye nobungakanani besuntswana elidlula kwisefu ye-mesh engama-80. Imilinganiselo eyahlukeneyo yomxholo we-methoxy kunye ne-hydroxypropyl kunye ne-viscosity yemveliso egqityiweyo yenza ukuba kube yindidi yeentlobo ezahlukeneyo kunye nokungafani ekusebenzeni. Ineempawu zokunyibilika kumanzi abandayo kwaye ayinyibiliki emanzini ashushu afana ne-methylcellulose, kwaye ukunyibilika kwayo kwi-solvents yezinto eziphilayo kudlula amanzi. Inokunyibilika kwi-anhydrous methanol kunye ne-ethanol, kunye ne-hydrocarbons eneklorini efana ne-dichloromethane, i-trichloroethane, kunye nezinyibilikisi ze-organic ezifana ne-acetone, isopropanol, kunye ne-diacetone alcohol. Xa inyibilika emanzini, idibanisa kunye neemolekyuli zamanzi ukwenza i-colloid. Izinzile kwi-acids kunye neziseko kwaye ayithinteki kwi-pH ye-2-12. Nangona i-hydroxypropyl methylcellulose ingeyotyhefu, iyatsha kwaye inokusabela ngobundlobongela kunye ne-oxidants [5].

I-viscosity yeiimveliso HPMCukwanda ngokunyuka koxinzelelo kunye nobunzima bemolekyuli. Xa iqondo lokushisa liphakama, i-viscosity iqala ukuhla. Xa iqondo lokushisa lifikelela kwiqondo elithile, i-viscosity iphakama ngokukhawuleza kwaye i-gel iyenzeka. Ubushushu be-gel yeemveliso ze-viscosity ephantsi ziphezulu kuneemveliso ze-viscosity eziphezulu. Isisombululo saso samanzi sizinzile kwiqondo lokushisa kwegumbi kwaye ngokuqhelekileyo asinako ukuthotywa kwe-viscosity ngaphandle kokuthotywa kwe-enzymatic. Ineempawu ezikhethekileyo ze-thermal gelling, ifilimu efanelekileyo yokwenza ifilimu kunye nomsebenzi ongaphezulu.

Ukulungiselela

Emva kokuba i-cellulose iphathwe nge-alkali, i-alkoxy anion eyenziwa yi-hydroxyl deprotonation inokongezwa kwi-epoxy propane ukuze ivelise.i-hydroxypropyl cellulose ether; Isenokujiya nge-methyl chloride ukuvelisa i-methyl cellulose ether. Xa zombini iimpendulo zisenzeka ngaxeshanye,i-hydroxypropyl methyl celluloseiveliswa.

injongo

Ukusetyenziswa kwei-hydroxypropyl methyl celluloseiyafana nezinyei-cellulose ethers, ikakhulu isetyenziswa njenge-dispersant, i-agent agent, i-thickener, i-emulsifier, i-stabilizer, kunye ne-adhesive kwiinkalo ezahlukeneyo. Iphezulu kunezinye i-cellulose ethers ngokwemiqathango yokunyibilika, i-dispersibility, i-transparency, kunye nokumelana ne-enzyme.

Kwishishini lokutya kunye namayeza, lisetyenziswa njengesongezo. Ngenxa yeempawu zayo zokubambelela, iipropati zokwenza ifilimu, ukuqina kunye nokusabalalisa kwi-liquids, kunye nokukwazi kwayo ukukhusela ukungena kweoli kunye nokugcina umswakama, isetyenziswe njenge-adhesive, thickener, dispersant, reliever, stabilizer, kunye ne-emulsifier. Ayinabutyhefu, ayinaxabiso lezondlo, kwaye akukho tshintsho lwemetabolism.

Ukwengeza,HPMCinee-aplikeshini kwi-synthetic resin polymerization reactions, i-petrochemicals, i-ceramics, i-papermaking, i-leather, i-cosmetics, i-cosmetology, izinto zokwakha, kunye neepleyiti zokuprinta ze-photosensitive.